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Tren Fat burning and fina cough both from prostaglandin metabolization
-It's been widely disussed of Trens fat burning properties through
rises in IGF and Prostaglandins. While IGF is a fairly well known
substance in the bodybuilding world today, prostaglandins are fairly
unknown in terms of formation and roles in the body.
So below, a brief dicription of prostoglandins and their role in fat
burning, "fina cough", and why a person going through Tren
administration can experience it's fat burning effects without the
dreaded "Cough"
The term prostaglandin comes from the word-Prostate. The first
prostoglandins were first dicovered in semen about the mid 1930's
and it was thought that prostaglandins were made from the prostate.
Since this time, it has been dicovered that most prostaglandins are
not even constructed in the prostate.
Prostaglandins are made by two different pathways(Cyclooxygenase and
Lipoxygenase), and considering prostaglandins are a group of about
20 lipid cells, they have contrary function; responsible for
stimulating as well as alleviating inflammation(Inflammation
stimulation is the rapid metabolism of them expelled through the
bronchials), regulate blood flow to particular organs, control ion
transport across membranes, modulate synaptic transmission, induce
sleep, mediate lipid release, and regulate metabolism is various
tissue.
Prostaglandins are synthesized from arachidonate(Lipoxygenase which
catalyze the dioxygenation of polyunsaturated fatty acids) in the
cell membrane by the action of phospholipase A2. Cyclooxygenase and
lipoxygenase pathways, compete with one another to form
prostaglandins(as well as thromboxane or leukotriene-leukotriene
being a bronchial stimulator),
In the cyclooxygenase pathway, the prostaglandins D, E and F plus
thromboxane and prostacyclin are made. Thromboxanes are made in
platelets and cause constriction of vascular smooth muscle and
platelet aggregation
Leukotrienes are made in leukocytes and macrophages via the
lipoxygenase pathway. They are potent constrictors of the bronchial
airways. They are also important in inflammation and
hypersensitivity reactions as they increase vascular permeability.
Being that prostaglandins from either pathway, are still fatty acids
of a group, they mediate lipid release and controll tissue
metabolization, so fat burning is a luxerry of either pathway of
formation. It's the pathway from which they are constructed that
dictates "fina cough". As prostaglandins made from the
Cyclooxygenase pathway dictate muscle constriction and platlet
aggregation, and the Lipoxygenase pathway dictates bronchial
constriction(the main form of expulsion)
by Pheedno
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