Glutamine/insulin/Growth Hormone connection
For those of you that are unaware, glutamine is the most highly
concentrated amino acid present in muscle tissue. A lack of it can be
severely detrimental, not only to training/growth, but overall health
as well (as it supports healthy immune system function). I've dug up
yet another interesting read from the notorious Dharkam on this
special amino acid, and drugs that work to effectively enhance its
absorption /prevent its escape. ENJOY.....
INSULIN TRANSPORTS GLUTAMINE
If some hormones cause glutamine depletion (cortisol being a primary
culprit), then others have the opposite effect. Insulin is your first
ally in glutamine manipulation. Glutamine is one of the few amino
acids whose entry into the muscle cell can be enhanced by insulin,
and you can certainly see the advantage of that. Any attempt to load
up on glutamine should take advantage of an insulin-boosting effect.
Some of the favorable actions of insulin are brought about by its
influence on sodium. Insulin helps your muscle cells get rid of the
extra sodium, which is a very interesting property in light of the
sodium invasion that normally follows training. What's more, the
anabolic effects of insulin and glutamine reinforce each other and
can only be maximum when both are present.
THE MIGHTY HGH
Human Growth hormone (GH) was made to work with glutamine, and vice versa.
Bodybuilders have long been aware of the close relationship between
the two because the fact that oral glutamine can increase GH. On the
other hand, they may not be aware that GH also increases glutamine
levels in both blood and muscles without the necessity of any
particular dietary alterations. Therefore, GH is truly the mighty
ally you're looking for in glutamine manipulation. One of the ways GH
works is to limit the wasting of glutamine in the liver, where it can
be transformed into urea. The urea is ultimately excreted in the
urine,which means the glutamine is wasted, simply because there's a
catabolic process at work. Research has shown that GH shunts the
"extracted glutamine nitrogen from urea via hapatic glutamate
release". The newly formed glutamate can be transformed into
glutamine in the muscle cells. So, instead of allowing glutamine to
be urinated as a waste product, GH favors the recycling of it. GH
also has another major preserving effect on glutamine in the kidneys.
One of the major reasons glutamine degradation is accelerated after
training is that lactic acid accumulates in the blood. That lowers
blood plasma pH and forces the kidneys to extract circulating
glutamine at a very fast pace. GH helps your kidneys to get rid of
the acid load and as a result reduces their need for glutamine. Oral
glutamine synergizes with GH at that point, not only by increasing
the GH level, but also by helping the hormone get rid of the lactic
acid that's generated by training. Other favorable effects of GH on
glutamine are brought about indirectly by the elevation of
Insulin-like growth-factor(IGF-1),a peptide that shares many of the
positive actions of insulin on glutamine.
Well, you fellas that are using GH and insulin should really consider
loading up on glutamine in conjunction with these hormones in the
future (if not already doing so)as you can see glutamine has the
ability to ENHANCE their performance, and vice versa.
As always, hope you guys enjoyed, and happy growing.....Huck
by: HUCKLEBERRY FINNaplex
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