what is Insulin-like Growth Factor-1
Usually Comes in 2 cc vials. This product is a freeze dried white
powder that requires refrigeration and is light sensitive. This
powder is supposed to be reconstituted with bacteriostatic water to
equal an amount of 2 cc. IGF-1 or insulin-like growth factor 1 is a
structural homologue of insulin that exhibits insulin-like activity.
IGF-1 is synthesized in the liver and it is bound to carrier proteins
that determine it's biological actions. IGF-1 is also the peptide
through which growth hormone exerts most of its growth promoting
effects. If you raise GH levels in the body, IGF-1 levels will also
rise. IGF-1 does have an effect on insulin production in the body. It
will lead to a decrease in insulin secretion which at the same time
increase insulin sensitivity. IGF-1 is chemically the same as insulin
but it is also somewhat different. IGF-1 does not seem to regulate
glucose levels in the body like insulin does though.
As far as bodybuilders are concerned, IGF-1 has several good effects.
It enhances nitrogen balance while simultaneously promoting fat loss.
Bodybuilders are claiming a 5% drop in bodyfat per month and huge
increases in strength. It also seems to lower LDL cholesterol. IGF-1
also normalizes hypoglycemia and hyperinsulinemia. It stimulates DNA
synthesis and cell multiplication. It might stimulate red-blood cell
production thereby increasing endurance. This action would be similar
to what EPO does for the body as well (see EPO description). It is
about 3 times less effective in this process as EPO in that respect.
EPO has bee used for years to increase oxygen utilization efficiency.
Bodybuilders have also found that IGF-1 reacts synergistically with
long duration testosterone's as well. Testosterone enanthate
increases serum IGF-1 levels in the body up to 21%.
When taken on its own, IGF-1 has a short half life. As is, the active
duration is only about 10 minutes in the body. Binding proteins added
to the compound seem to extend the half-life dramatically. When
coupled with IGFBP-3 (IGF binding protein-3), the half-life is
extended to between 6 and 16 hours which is a much more usable time
duration. This product is very hard to get ahold of as well. Most
people will probably never even see a vial of this stuff. It is only
made by three pharmaceutical companies in the world. To get some of
this, you have to be either a research student or know someone who
knows someone, who knows someone....if you can find it, IGF-1 will
cost you between
20 to 60mcgs every other day.
It is commonly stacked with insulin, growth hormone, and any and all
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