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1.What is Clenbuterol and how does it work?
Simply put, Clenbuterol hydrochloride (the full chemical name for Clenbuterol) is a beta-2-adrenergic agonist, and was initially used to treat asthma in humans. Other such drugs in this class are albuterol (I believe this is brand named as Ventolin, the blue inhaler commonly seen), pirbuterol, terbutaline and salmeterol.

Clenbuterol has two secondary effects that are beneficial to athletes and bodybuilders. The first is a strong anti-catabolic effect, which means it decreases the rate at which protein is used up in the muscle cells, consequently causing hypertrophy of muscle cells (with proper training, of course). Clen accomplishes this by the stimulation of both type 2 and 3 beta-receptors. 3-beta receptors are more abundant in livestock than in humans. This explains the pronounced anabolic effects on livestock as opposed to humans.

Secondly, Clen has a wonderful thermogenic effect. This is the main reason that is included in nearly every cutting cycle in some form or fashion. This means that it slightly raises the body temperature of the person taking it. When the body's temperature rises it burns fat more productively. When stacked with an LT-3 hormone such as Cytomel, the body turns into the fiery pits of hell and burns fat like a stripper scoops up dollar bills on a Friday night.

Clenbuterol is known by the following brand names:
Broncodil, Broncoterol, Cesbron, Clenasma, Clenbuter.Pharmachim, Contrasmina, Contraspasmina, Monores, Novegam, Oxyflux, Prontovent, Spiropent, Ventolase, and Ventapulmin It is generally available in 10 - 20 mcg tablets, although syrup, injectables and "Super Clen" (x20 the normal dosage of normal tabs) are also
somewhat popular.

2. Will Clenbuterol help me if I am on AS?
Yes, particularly at the end of a cycle to keep gains. Bodybuilders use Clenbuterol after steroid cycles to balance the resulting catabolic phase following a cycle and to retain strength and muscle mass. Also, as a result of the higher body temperatures, Clenbuterol magnifies the effect of anabolic/androgenic steroids taken simultaneously, since the protein processing is increased. ???2

(Taken from "When these agonists bind to beta-2 adrenoceptors,
they activate adenyl cyclase which leads to an increase in the intracellular concentration of the second messenger cyclic adenosine monophosphate (cAMP) and activation of protein kinase A (PKA). In the tracheobronchial tree, beta-2 agonists, cAMP and PKA inhibit smooth muscle contraction by opening K+ channels and by down-regulation of myosin light chain kinase activity." ???1

In the airways, beta-2 adrenoceptors are not restricted to smooth muscle. They also occur on epithelium, inflammatory cells, and the vasculature. When epithelial beta adrenoceptors are activated, cilliary beat frequency increases. The effect on mucus secretion is less consistent, but the weight of opinion indicates that beta-2 agonists increase mucocillary clearance. Activation of beta-2 adrenoceptors on inflammatory cells reduces the release of inflammatory mediators, and activation of those in vasculature can inhibit the permeability increase that occurs in inflammation. Thus making it easier to breath.

3. Will Clenbuterol help me burn fat?
Hell yes and no. The yes is stated above--Clen is a strong thermogenic. Diet and cardio are most important in this process (of course), as is a good weight training regimen. If one keeps a clean diet, does regular cardio (3-4+ times a week) then Clenbuterol will greatly assist in fat loss. If one sits around the couch all day, eats empty calories like sugars and simple carbs, Clenbuterol will be as useful as a sugar pill.

4. What is the recommended dosage for Clenbuterol?
This has become a matter of controversy among the Bodybuilding community. Due to erroneous assumptions based on livestock dosing based on the types of receptors that humans and livestock have , 2 days on-2 days off was thought to be the proper dosage. Given Clenbuterols half-life of about 10 hours, with a 2-days on/2-days off cycle you never have time to get enough of the clenbuterol out of your system for this to be an effective cycle. In actuality, it probably hasn't even dropped to 50% of your peak concentration before one is taking the drug again. With this all taken into account, there is no reason to think that this cycling would significantly reduce the problem of receptor desensitization. 2-weeks on/2-weeks off is a better cycle, with ECA stacked in between.

At a dosage of around 5-7 tablets or 100-140 mcg per day for men over a period of 8-10 weeks. In females, dosages of 80-100 mcg/day are usually sufficient. For fat loss, clenbuterol seems to stay effective for 3-6 weeks, then its thermogenic properties seem to subside. This is noticed when the body temperature drops back to normal. Its anabolic properties subside much quicker, somewhere around 18 days. Also keep in mind that anything over 140 mcg a day is useless since the beta receptors can only handle so much. ???

4. Should I taper Clenbuterol on and off?
Yes. With ANY thermogenic, the side effects can be pronounced and a shock to the system. To lessen these, here is an optimal pill count for a two-week cycle. (assuming standard Clen dosages of 20mcg such as Spriopent).

Week 1: 2, 3, 4, 5, 6, 6, 6
Week 2: 6, 6, 6, 5, 4, 3, 2

Weeks 3 and 4: ECA (Hydroxycut, Xenadrine, Stacker, etc.)
The ECA stacks in between will help prevent against the inevitable crash when taking Clen.

5. What are some of Clenbuterol's side effects?
Possible side effects of Clenbuterol include restlessness, palpitations, tremor (involuntary trembling of fingers), headache, increased perspiration, insomnia, possible muscle spasms, increased blood pres-sure, and nausea. Note that these side effects are of a temporary nature and usually subside after 8-10 days, despite continuation of the product.


Q: Can I substitute Ventolase or another asthma medication for Clenbuterol since they are the same category?

A: No. Remember that the only reason the FDA banned Clenbuterol was because of the long half-life. Well approved asthma medications have very short half-lives. Therefore, the effective dosage period is very low.

Q: Will Clenbuterol give me gyno, masculinization, shrinkage of the boys or any steroid-like side effect?
A: No. Clenbuterol has no steroid-like side-effects as the mechanisms are totally different. This also means that you do not have to take Clomid or any anti-estrogen during a Clenbuterol cycle.

Q: Will Clenbuterol show up on a drug test?
A: Only if you are being tested by a body that bans it. This is generally international competition such as the Olympics. Employment, doctors physicals, military does NOT test for this. The NCAA is reputed not to, however this is unknown. It is best to get a prescription from a doctor for asthma medication. Ventolin, Albuterol and the like trigger the same tests as Clenbuterol. With a doctors prescription for one of these similar products, the Clen will be seen as a false positive.

Q: I've read that the best way to gauge Clenbuterol's effectiveness is to watch for a rise in temperature. Is this true?
A: Although this will show when Clenbuterol is working, it is not the best way to gauge effective dosage, as everyone's body will react differently. This reaction is sometimes independent of an effective dosage and is not a good way to gauge if your current dose is effective. The above cycle is based on a< 175-lb man. If you are below that, you may want to slightly decrease the dosage if you find the shakes to be unbearable after 4-5 days.
Q: What are "Street" prices?
A: Though your mileage may vary, if you are paying more than US $.50 a pill, you are seriously getting the shaft.

by Nick Bockwinkle
First off, I would like to give a big hoot to the guys on FitnessBoard /Steroids101. Small for his kickass "Liquid Fury" Cycle, GearedUp for being a kickass mod, Lewd Tennant (you da man), CJ, f41, Chesta and all of you who make that board a great place to be!!

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